Real Madrid have difficult time and a win against Alaves is a must. They lost to Manchester City in a match where they didn't deserve to lose, but they wasted too many points in Primera and let Barcelona go 7 points above them. Xabi Alonso still has injury concers, especially in defense. Huijsen may feature, while Militao, Alexander-Arnold, Mendy and Carvajal remain out. When we add suspended Carreras and Fran Garcia, we can conclude that Rudiger and Courtois might have difficulties. Mbappe is also doubtful, but some players like Valverde and Rodrygo played really good, but could not break City.
Alaves are very tough opponents, they play with low goals and have more focus on defense. Only Villareal conceded less goals than Alaves which says enough about their defense.
Real is a team with atomic attack and weak defense. If their midfield dominates against Alaves, Real won't have big issues.