This bet will be going against Cerro Porteno, not because they are a bad side, but simply due to schedule complications and priorities. Cerro are going to Venezuela to face Monagas away in a highly important Copa Libertadores qualifiers. It is essential to secure a good enough result here.
Cerro will then fly to Asuncion, to face Olimpia, away, 3 days later. The time is not bad, but you can safely assume that their squad will consist of some rotations and bench players, in order for the return leg against Monagas to be the game of priority that week.
Olimpia have no such scenarios to consider, so they will hungrily await the match against Cerro. They are the best home team in Paraguay. The games against Cerro are usually closely contested, with 1-4-0 on this stadium in the last 5 meetings. They have opened the Apertura with 10 goals in 5 matches, collecting 3 consecutive victories.
Conclusion: Olimpia should have great chances here of securing a good result. Cerro will have two flights to Venezuela, a game extra, and need to manage their squad more carefully. Olimpia at home should take advantage. Currently 1.80 for DNB is enticing. Expecting this to be something around 1.60 by match time