Early bet as odds are likely to generally drop in the next days.
Motagua are horrible so far on all fronts, lost all 3 games in the CL with big margin and after 2-4 at home from Alajuelense last midweek out of the contest. Hard to expect that their morale and motivation will be at top level for this game. Besides that Motagua started very poor also in their domestic league, after 6 rounds last in the table. All this resulted in kicking out the coach Ramón Maradiaga 4 days ago and still there is no new man in charge. In this situation quite probably Motagua may rest some players for the weekend game with Deportes Savio trying to bounce back at least on the domestic scene. That will be even better as I bet against them no matter of who will appear on the pitch.
Morelia are in contest with LA Galaxy and Alajuelense for the first 2 places, all of them with 6 pts. As usually, there will be a serious rotation of players compared with the lineup used in Primera but this is not any piece of worry as Morelia have a very deep squad and good options for every position. In the reverse game this "midweek" selection didn't have any problems with Motagua and thumped them with 4-0.