Quite big handicap considering that both teams have similar level and Peru are not a team to be scared of playing in Ecuador (meaning the altitude of Quito). Since 2000 Peru stayed unbeated in 3 from total 5 visits in Ecuador.
The NT of Ecuador is far from its best years, latest seen on Copa America where they finished last in their group with just 1 point after 3 games. After Copa America Ecuador got a string of wins in friendlies but mostly against fringe selections, still not enough to convince us that Antonio Valencia (the only one playing on highest international level) and the bulk of players for the local and Mexican league are rising for something big. So far Ecuador played 2 World Cup qualifiers, win at home vs Venezuela and loss in Paraguay few days ago.
Peru haven't been shining since long tme but after clearing some internal problems in their football and with Sergio Markarian in charge looking a lot better. Even ravaged with injuries of key players Peru managed to get 3rd on Copa America. As Ecuador, with a win (vs Paraguay) and a loss (in Chile) in the first two qualifiers, the difference is that Peru didn't play in the weekend and had quite long time to prepare for today (in Lima and Arequipa to get fit to altitude), all best players are at disposal. It is certain that Peru have enough quality in midfield and attack to upset any team with Juan Vargas, Jefferson Farfán, Claudio Pizarro and Paolo Guerrero who playing together don't miss to score. There is quite high spirit and optimism in Peru for this game and even as Ecuador are still sort of favorites at home the odds are inviting for this bet.