1x2 odds reversed for this game - Itagui started as favorites and now clearly pointed underdogs, as some people like to say big "public" bet on Atletico Nacional so preferring to stay away from backing a side but the u/o odds are quite appealing. I don't see why bookies expect low scoring game, Atletico Nacional are known with their offensive style, scoring a lot of goals and not so strict at the back, last year 60% of their total 58 games ended over 2.5 (the ratio could be even higher if they haven't lost motivation with the run of Liga Postobon II). Similar picture expected this season too, the team kept both topscorers Dorlan Pabon (17 goals) and Carlos Renteria (16 goals) and even strengthened further in the front line with Johan Fano (Universitario) and Luis Mosquera (attacking midfielder, 14 goals last season for DIM). In the first round los verdolagas beated Deportivo Cali by 4-0 (Pabon's hattrick showing he's still in great form). All important players are available for tonight.
Hard to say what to expect from Itagui, modest team that did quite fine last year but they lost almost all players who were used in defense, it wasn't fatal in the first round against the quite impotent La Equidad but today this may be a serious problem against the rocket attack of Atletico Nacional. In 2011 52% of the games of Itagui went over 2.5 (3 from their total 4 mutual games with Atletico Nacional finished over 2.5 with total 13 goals scored) so even on their side it's hard to see a reason why the Asian goal line is 2.25.